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RXR |
LOCUS ID | 0 | ||||||||||
GENE_SYMBOL | RXR | ||||||||||
GENE NAME | |||||||||||
SYNONYMNS | |||||||||||
CHROMOSOME | |||||||||||
HOMOLOGENE ID | 0 |
microRNAs | NA | NA |
GENE SUMMARY |
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Retinoid X receptors (RXR) are members of the NR2B nuclear receptor family and are common binding partners to many other nuclear receptors, including PPARs, liver X receptors (LXRs) and vitamin D receptors (VDRs). There are three RXR subtypes; alpha, beta and gamma. |
OBSERVATIONS |
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Complication | Evidence | PMID |
Tuberculosis | 1. Repression of RXR gene could hamper VDR-RXR heterodimer formation and thus would up regulate TACO gene expression which may predispose the type-2 DM patients to tuberculosis. | 26089620 |