S100A4
LOCUS ID6275
GENE_SYMBOLS100A4
GENE NAMES100 calcium binding
SYNONYMNS42A 18A2 CAPL FSP1 MTS1 P9KA PEL98
CHROMOSOME1
HOMOLOGENE ID7924
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosom

OBSERVATIONS

Complication Evidence PMID
Insulin resistance and inflammation1. S100A4 sWAT expression associated positively with genes involved in inflammation/extracellular matrix formation and inversely with genes in metabolic pathways. 29453465