| S100A8 |
| LOCUS ID | 6279 | ||||||||||
| GENE_SYMBOL | S100A8 | ||||||||||
| GENE NAME | S100 calcium binding | ||||||||||
| SYNONYMNS | P8 MIF NIF CAGA CFAG CGLA L1Ag MRP8 CP-10 MA387 60B8AG | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 2225 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altere |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Significant increase of S100A8 was detected in mature adipocyte fraction just 5 d after HF/HS diet | 25848057 |