| S100A9 |
| LOCUS ID | 6280 | ||||||||||
| GENE_SYMBOL | S100A9 | ||||||||||
| GENE NAME | S100 calcium binding | ||||||||||
| SYNONYMNS | MIF NIF P14 CAGB CFAG CGLB L1AG LIAG MRP14 60B8AG MAC387 | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 2227 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. S100A9-deficient neutrophils exhibited a reduced secretion of cytokines in response to toll-like receptor-4 stimulation. | 21382888 |