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SCAMP3 |
LOCUS ID | 10067 | ||||||||||
GENE_SYMBOL | SCAMP3 | ||||||||||
GENE NAME | secretory carrier me | ||||||||||
SYNONYMNS | C1orf3 | ||||||||||
CHROMOSOME | 1 | ||||||||||
HOMOLOGENE ID | 4164 |
microRNAs | NA | NA |
GENE SUMMARY |
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This gene encodes an integral membrane protein that belongs to the secretory carrier membrane protein family. The encoded protein functions as a carrier to the cell surface in post-golgi recycling pathways. This protein is also involved in protein trafficking in endosomal pathways. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Insulin resistance and inflammation | 1. PPARG and SCAMP3 exhibited opposite behaviors regarding correlations with clinical phenotypes, including body mass index, body fat mass, adipocyte size, lipolytic and lipogenic capacity, and secretion of pro-inflammatory cytokines. | 31554889 |