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SCX |
LOCUS ID | 642658 | ||||||||||
GENE_SYMBOL | SCX | ||||||||||
GENE NAME | scleraxis bHLH trans | ||||||||||
SYNONYMNS | SCXA, SCXB, bHLHa48 | ||||||||||
CHROMOSOME | 8 | ||||||||||
HOMOLOGENE ID | 85195 |
microRNAs | NA | NA |
GENE SUMMARY |
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SCX (Scleraxis BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with SCX include Anomalous Left Coronary Artery From The Pulmonary Artery and Peroneal Neuropathy. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and protein dimerization activity. An important paralog of this gene is TCF15. |
OBSERVATIONS |
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Complication | Evidence | PMID |
Nephropathy | 1. These data suggest that Scx and Id1 are involved in the BMP4-Smad1-SMA signal transduction pathway besides the TGF beta 1-Smad1-SMA signaling pathway and modulate phenotypic changes in MCs in diabetic nephropathy. | 22474292 |