| SGK3 |
| LOCUS ID | 23678 | ||||||||||
| GENE_SYMBOL | SGK3 | ||||||||||
| GENE NAME | serum/glucocorticoid | ||||||||||
| SYNONYMNS | CISK, SGK2, SGKL | ||||||||||
| CHROMOSOME | 8 | ||||||||||
| HOMOLOGENE ID | 56582 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alterte transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. SGK2 and SGK3 mRNA were elevated in DN mice. | 16116964 |