| SLC19A1 |
| LOCUS ID | 6573 | ||||||||||
| GENE_SYMBOL | SLC19A1 | ||||||||||
| GENE NAME | solute carrier famil | ||||||||||
| SYNONYMNS | RFC CHMD FOLT IFC1 REFC RFC1 hRFC IFC-1 MEGAF RFT-1 hSLC19A1 | ||||||||||
| CHROMOSOME | 21 | ||||||||||
| HOMOLOGENE ID | 57139 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. SLC19A1 knockdown in human adipocytes perturbed intracellular 1CC metabolism, induced global DNA hypermethylation, and increased expression of proinflammatory genes. | 29121255 |