| SLC30A8 |
| LOCUS ID | 169026 | ||||||||||
| GENE_SYMBOL | SLC30A8 | ||||||||||
| GENE NAME | solute carrier famil | ||||||||||
| SYNONYMNS | ZNT8, ZnT-8 | ||||||||||
| CHROMOSOME | 8 | ||||||||||
| HOMOLOGENE ID | 13795 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Nephropathy | 1. Polymorphisms of SLC30A8 and TCF7L2 genes may be associated with the development of DR and DN, respectively. Association between the polymorphisms of CKDAL1, TCF7L2 and HHEX genes and DR, and between the polymorphisms of SLC30A8, HHEX and CDKAL1 genes and DN, cannot be excluded. | 22487833 |