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TINCR |
LOCUS ID | 257000 | ||||||||||
GENE_SYMBOL | TINCR | ||||||||||
GENE NAME | TINCR ubiquitin doma | ||||||||||
SYNONYMNS | PLAC2 LINC00036 NCRNA00036 onco-lncRNA-16 | ||||||||||
CHROMOSOME | 19 | ||||||||||
HOMOLOGENE ID | 0 |
microRNAs | NA | NA |
GENE SUMMARY |
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This gene produces a spliced long non-coding RNA that binds RNAs. This transcript interacts with staufen-1 protein to regulate the stability of mRNAs for genes involved in the differentiation of epidermal tissue. Variation in this gene may be associated with cancer progression. [provided by RefSeq, Aug 2017] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Insulin resistance and inflammation | 1.lnc TINCR is a positive regulator of inflammation-induced insulin resistance presumably via activation of NOD1 signaling pathways. | 30851423 |