| TMEM26 |
| LOCUS ID | 219623 | ||||||||||
| GENE_SYMBOL | TMEM26 | ||||||||||
| GENE NAME | transmembrane protei | ||||||||||
| SYNONYMNS | |||||||||||
| CHROMOSOME | 10 | ||||||||||
| HOMOLOGENE ID | 14428 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a protein containing multiple transmembrane helices. It is a selective surface protein marker of brite/beige adipocytes, which may coexist with classical brown adipocytes in brown adipose tissue. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1.In cohort 1, VAT?NRG4?gene expression was positively correlated with BMI and expression of?UCP1, UCP3, TMEM26, and negatively with adipogenic (FASN, PPARG, and?SLC2A4)- and inflammatory (IL6 and IL8)-related genes. | 30766490 |