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TRPA1 |
LOCUS ID | 8989 | ||||||||||
GENE_SYMBOL | TRPA1 | ||||||||||
GENE NAME | transient receptor p | ||||||||||
SYNONYMNS | FEPS, ANKTM1 | ||||||||||
CHROMOSOME | 8 | ||||||||||
HOMOLOGENE ID | 7189 |
microRNAs | NA | NA |
GENE SUMMARY |
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The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Neuropathy | 1. The indicate that the TRPA1 channel exerts an important role in the pathogenesis of peripheral diabetic neuropathy (PDN). Blocking the TRPA1 channel provides a selective disease-modifying treatment of PDN. | 22133672 |