| TRPV3 |
| LOCUS ID | 201131 | ||||||||||
| GENE_SYMBOL | TRPV3 | ||||||||||
| GENE NAME | Transient Receptor P | ||||||||||
| SYNONYMNS | NA | ||||||||||
| CHROMOSOME | 17 | ||||||||||
| HOMOLOGENE ID | 17040 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Neuropathy | 1. The accumulation of TRPV1 and TRPV3 in peripheral nerves after injury, in spared axons, matches our previously reported changes in avulsed DRG. | 17521436 |