| USF2 |
| LOCUS ID | 7392 | ||||||||||
| GENE_SYMBOL | USF2 | ||||||||||
| GENE NAME | upstream transcripti | ||||||||||
| SYNONYMNS | FIP, bHLHb12 | ||||||||||
| CHROMOSOME | 19 | ||||||||||
| HOMOLOGENE ID | 2527 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Nephropathy | 1. These findings suggest that overexpression of USF2 accelerates the development of diabetic nephropathy. | 17881461 |