| USP10 |
| LOCUS ID | 9100 | ||||||||||
| GENE_SYMBOL | USP10 | ||||||||||
| GENE NAME | ubiquitin specific p | ||||||||||
| SYNONYMNS | UBPO | ||||||||||
| CHROMOSOME | 16 | ||||||||||
| HOMOLOGENE ID | 31294 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human ge |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1.Conclusion: USP10 inhibits hepatic steatosis, insulin resistance, and inflammation through Sirt6. | 29698567 |