| UTS2R |
| LOCUS ID | 10893 | ||||||||||
| GENE_SYMBOL | UTS2R | ||||||||||
| GENE NAME | urotensin 2 receptor | ||||||||||
| SYNONYMNS | UTR, UTR2, GPR14, UR-2-R | ||||||||||
| CHROMOSOME | 17 | ||||||||||
| HOMOLOGENE ID | 10345 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| UTS2R (Urotensin 2 Receptor) is a Protein Coding gene. Diseases associated with UTS2R include Pheochromocytoma and Rhabdomyosarcoma. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and urotensin II receptor activity. An important paralog of this gene is SSTR5. |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. diabetes-induced upregulation of UII and GPR14, most likely through autocrine and/or paracrine mechanisms, plays an important role in TGF-beta1-mediated renal fibrosis and dysfunction. | 18796544 |