| WNT5A |
| LOCUS ID | 7474 | ||||||||||
| GENE_SYMBOL | WNT5A | ||||||||||
| GENE NAME | Wnt family member 5A | ||||||||||
| SYNONYMNS | hWNT5A | ||||||||||
| CHROMOSOME | 3 | ||||||||||
| HOMOLOGENE ID | 20720 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1.WNT5A, a non-canonical WNT ligand, has been shown to promote adipose tissue inflammation and insulin resistance in animal studies. | 29229927 |