A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders
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Gene 1 | Gene 2 | SNP_Id | Allele | Chromosome | Chromosome Position | Functional Class | P-Value | Odds Ratio | PMID |
---|---|---|---|---|---|---|---|---|---|
ABCA1 | rs9282541 | R230C | 9 | 104858554 | missense,reference | 3.3 * 10-6 | 3.3776 | 18003760 | |
ADRA2A | rs553668 | A>G / A>T | 10 | 111079821?( | ADRA2A : 3 Prime UTR Variant | 95% CI of 2 | 3.64 | 29800730 | |
ADRB3 | rs4994 | Arg/Trp | 8 | 37823798 | missense,reference | 0.001 | 0.62 | 20503258 | |
CDKN2A | CDKN2B | rs10811661 | T | 9 | 22134094 | -- | 0.001 | 1.42 | 20503258 |
HNF4A | rs1800961 | T/I | 20q | 44413724 | missense_variant,reference | 0.049 | 28688048 | ||
IRS1 | rs1801278 | -- | 2 | 227660544 | missense,reference | -- | 2.43 | 20503258 | |
KCNJ11 | rs5210 | G | 11 | 9.6*10-5 | 28352326 | ||||
KCNQ1 | rs2237892 | C | 11 | 2839751 | intron-variant | 0.001 | 1.36 | 20503258 | |
PLA2G2A | rs3753827 | A | 1 | 19979394 | intron-variant | Pcodom1=0.0 | OR(codo | 27608594 | |
PLA2G2A | rs11573156 | C | 1 | 19979653 | intron-variant,utr-variant-5-prime | Pcodom1=0.0 | OR(codo | 27608594 | |
PPP1R3A | rs1799999 | C>A | 7 | 113878379 ( | PPP1R3A : Missense Variant | 0.014 | 1.625 | 29948331 | |
SIRT1 | rs3758391 | C/T | 10 | 69643342 | upstream-variant-2KB | 0.031 | 1.32 | 20503258 | |
SLC16A11 | rs13342232 | G | 17 | 7042621 | intron-variant,reference,synonymous-codon | P(adults)=0 | ORadj(a | 28101933 | |
TCF7L2 | rs7903146 | C/T | 10 | 114758349 | intron-variant | 0.001 | 1.76 | 20503258 | |
TCF7L2 | rs12255372 | G/T | 10 | 114808902 | intron-variant | 0.002 | 1.78 | 20503258 | |
TNFA | rs361525 | - 238G/A' | 6 | 31575324 | upstream-variant-2KB | 0.018 | 1.57 | 21508505 |