A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders
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Gene | SNP_Id | Allele | Chromosome | Chromosome Position | Functional Class | P-Value | Odds Ratio | PMID |
---|---|---|---|---|---|---|---|---|
ACSL1 | rs735949 | 26711138 | ||||||
ADIPOQ | rs16861205 | A | 0.003 | 26699120 | ||||
ADRB3 | -- | Ile62Met | 8 | -- | -- | 0.01 | -- | 16444766 |
ARHGEF11 | -- | R1467H | 1 | -- | -- | 0.01 | 3.39 | 17287471 |
BARX2 | rs7107217 | C | 11 | 129603795 | 0.0000003 | 1.18 | 22238593 | |
C14orf70 | rs730570 | G | 14 | 100676553 | 0.000008 | 1.14 | 21573907 | |
CACNA1E | G/A 3'UTR | 1 | -- | -- | 2.09 | 0.001 | 17720895 | |
CDKN2A | rs1333051 | A | 9 | 22136490 | 6.00E-10 | 1.22 | 21573907 | |
CHRM3 | rs3738435 | C | 1 | 239907303 | intron-variant | 0.00006 | -- | 17130513 |
CREBRF | rs373863828 | G>A | 5 | 173108771?(GRCh38.p12) | CREBRF : Missense Variant | p = 1.9 ? 10-6 | 0.59 | |
CYB5A | rs7238987 | T | 18 | 74260915 | intron-variant | 6.20E-07 | 24151200 | |
DNER | rs1861612 | T | 2 | 229657682 | intron-variant | 6.60E-08 | 1.29 | 24101674 |
FABP2 | 26703680 | |||||||
FGF23 | 26693712 | |||||||
GALNTL4 | rs2722769 | C | 11 | 11206827 | 0.000002 | 1.35 | 22238593 | |
HNF1A | rs7305618 | C | 12 | 120965129 | 0.00000002 | 1.14 | 21573907 | |
IGF2BP2 | rs1374910 | T | 3 | 185813873 | intron-variant | 0.0000001 | 1.24 | 21573907 |
IKBKB | 4.00E-08 | 26757982 | ||||||
INS | 26950197 | |||||||
IRS1 | -- | -446 G/A | 2 | -- | -- | -- | -- | 14633864 |
KCNJ10 | Glu359Lys | 12401729 | ||||||
KCNK16 | rs1544050 | 0.002 | 1.16 | 27862917 | ||||
KCNQ1 | rs8181588 | T | 11 | 2810311 | intron-variant | 0.000000005 | 1.3 | 24101674 |
KCNQ1 | rs2237892 | C | 11 | 2818521 | intron-variant | 0.000004 | 1.2 | 21573907 |
MYO5A | rs34602777 | C | 15 | 52503597 | intron-variant | 0.0097 | -- | 22791750 |
OPRM1 | rs648007 | A | 6 | 154101476 | intron-variant | 0.013 | -- | 16140553 |
PFDN2 | 0.0001 | 1.27 | 28731290 | |||||
PTGS2 | rs20417 | C | 1 | 186681189 | upstream-variant-2KB | 0.001 | 1.6 | 12920574 |
PTPRD | rs649891 | C | 9 | 10430602 | intron-variant | 0.000006 | 21647700 | |
RBM43 | rs7560163 | C | 2 | 150781422 | 0.000000007 | 1.33 | 22238593 | |
RNF10 | C | 12 | -- | -- | 7.20E-04 | 24151200 | ||
SC4MOL | rs17046216 | A | 4 | 165334552 | intron-variant | 2.90E-08 | -- | 22791750 |
SIRT1 | rs10509291 | T | 10 | 69635204 | -- | 0.01 | 1.25 | 21871827 |
SIRT1 | rs7896005 | G | 10 | 69651125 | intron-variant | 0.02 | 1.17 | 21871827 |
SLC44A3 | rs7542900 | C | 1 | 94604485 | 0.000006 | 1.16 | 22238593 | |
TBC1D4 | 5.4 | 27561922 | ||||||
TCERG1L | rs7077836 | T | 10 | 132751498 | -- | 4.90E-10 | -- | 22791750 |
TCF7L2 | rs7903146 | C/T | 10 | 114758349 | intron-variant | 4.10E-06 | 1.51 | 17601994 |
TCF7L2 | rs7901695 | T/C | 10 | 114754088 | intron-variant | 0.001 | 0.003 | 17601994 |
TLR4 | rs4986790 | 0.025 | 27648011 | |||||
WFS1 | rs10010131 | G | 4 | 6291188 | intron-variant | 0.08 | -- | 22513821 |