T2DiACoD

A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders

Gene	Gene 2	SNP_Id	Allele	Chromosome	Chromosome Position	Functional Class	P-Value	Odds Ratio	PMID
7 kb upstream		rs9942471	A>C	6	89238513?(G	None	2.1 X 10-7	1.24	29703844
ADAMTS9		rs4607103	C	3	64726228	intron	0.00000001	1.09	18372903
ANXA5	TMEM155	rs7659604	T	4	121744359	--	0.000009	1.35	17554300
BCL11A		rs243021	A	2	60357684	--	3.00E-15	1.08	20581827
CACNA1E		rs679931	TT	1	181514928	intron-variant	0.06	1.4	17934712
CCND2		rs76895963	G	12	4275678	intron-variant	4.40E-10	0.55	24464100
CCND2		rs75615236	G	12	4196806	--	7.90E-05	1.15	24464100
CD96		rs1282090	A/G	3	111578267	intron-variant	0.0004	1.58	17846126
CDC123	CAMK1D	rs12779790	G	10	12286011	--	1.00E-10	1.11	18372903
CDKAL1		rs10946398	--	6	20660803	intron	0.0000007	1.18	19056611
CDKAL1		rs10946398	C	6	20661034	intron-variant	4.10E-04	1.12	20424228
CDKAL1		rs10440833	A	6	20687890	intron	2.00E-22	1.25	20581827
CDKAL1		rs6931514	G	6	20703721	intron	1.00E-11	1.25	18372903
CDKAL1		rs9465871	C	6	20717024	intron	0.0000003	1.18	17554300
CDKAL1		rs7754840	C	6	20661019	intron	4.00E-11	1.12	17463246
CDKAL1		rs7756992	G	6	20679478	intron	0.000000008	1.2	17460697
CDKAL1		rs10946398	C	6	20660803	intron	0.00000001	1.16	17463249
CDKN2A	CDKN2B	rs10811661	T	9	22134095	--	0.000005	1.19	17463249
CDKN2A	CDKN2B	rs564398	T	9	22029548	ncRNA	0.000001	1.13	17463249
CDKN2A	CDKN2B	rs10965250	G	9	22133285	--	1.00E-10	1.2	20581827
CDKN2A	CDKN2B	rs7020996	C	9	22129580	--	0.0000002	1.26	18372903
CDKN2A	CDKN2B	rs10811661	T	9	22134095	--	0.00000005	1.2	17463246
CDKN2B		rs10811661	--	9	22134095	--	0.0000007	1.26	19056611
CENTD2		rs1552224	A	11	72722053	intron	1.00E-22	1.14	20581827
CHCHD9		rs13292136	C	9	79337213	--	0.00000003	1.11	20581827
COL13A1		rs4082516	C/G	10	69944900	intron-variant	3.19E-05	0.53	17846126
DCD		rs1153188	A	12	54705212	--	0.0000002	1.08	18372903
DUSP9		rs5945326	A	23	153634467	--	3.00E-10	1.27	20581827
FBXL17		rs723397	C/T	5	108012342	intron-variant	0.0003	0.65	17846126
FLJ34870		rs9287428	C/T	2	133438497	intron-variant	0.0002	1.62	17846126
FLJ34870		rs7604549	A/G	2	133449192	intron-variant	0.0002	0.65	17846126
FTO		rs1421085	C	16	53800954	intron-variant	0.02	--	19255736
FTO		rs11642841	A	16	53811575	intron	0.00000003	1.13	20581827
FTO		rs8050136	--	16	53782363	intron	2.00E-17	1.3	19056611
FTO		rs8050136	A	16	53782363	intron	0.000007	1.15	18372903
FTO		rs9939609	A	16	53786615	intron	0.0000002	1.34	17554300
FTO		rs8050136	A	16	53782363	intron	7.00E-14	1.23	17463249
GFM1		rs1492908	A/G	3	158668718	intron-variant	0.0002	0.62	17846126
GFM1		rs1367313	C/T	3	158647749	intron-variant	0.0003	1.57	17846126
Grb10		rs2237457	A/G	7	50658447	intron-variant	1.07E-05	0.61	17846126
HHEX		rs1111875	G/A	10	94462882	--	5.70E-10	1.13	20424228
HHEX		rs5015480	C	10	92705802	--	0.00000007	1.17	18372903
HHEX		rs1111875	C	10	92703125	--	6.00E-10	1.13	17463246
HHEX		rs5015480	C	10	92705802	--	0.000005	1.13	17463249
HHEX		rs1111875	G	10	92703125		0.000003	1.19	17293876
HHEX	IDE	rs5015480	C	10	92705802	--	1.00E-15	1.18	20581827
HIGD1C		rs12304921	G	12	50963759	intron	0.000007	2.5	17554300
HMGA2		rs1531343	C	12	65781114	intron	0.000000004	1.1	20581827
HNF1A		rs7957197	T	12	121022883	intron	0.00000002	1.07	20581827
HNF1B	TCF2	rs4430796	G	17	37738049	intron	0.000002	1.14	20581827
IGF2BP2		rs1470579	C	3	185811292	intron	0.000000002	1.14	20581827
IGF2BP2		rs4402960	T	3	185793899	intron	0.00000008	1.17	18372903
IGF2BP2		rs4402960	T	3	185793899	intron	0.000000002	1.17	17463246
IGF2BP2		rs4402960	T	3	185793899	intron	9.00E-16	1.14	17463249
IGF2BP2		rs4402960	T/G	3	185511687	intron-variant	--	--	20424228
IL10		rs1800896	1082 A>G						27114918
IRS1		rs7578326	A	2	226155937	intron	5.00E-20	1.11	20581827
JAZF1		rs864745	A	7	28140937	intron-variant	0.03	1.08	19020324
JAZF1		rs849134	A	7	28156603	intron	0.000000003	1.13	20581827
JAZF1		rs864745	T	7	28140937	intron	5.00E-14	1.1	18372903
KCNJ11		rs5219	T>C	11	17409572	intron-variant,missense,reference	6.70E-04	1.14	20424228
KCNJ11		rs5219	--	11	17388025	missense	0.0000005	1.19	19056611
KCNJ11		rs5215	C	11	17387083	missense	0.0000004	1.16	18372903
KCNJ11		rs5219	T	11	17388025	missense	0.0000001	1.15	17463246
KCNJ11		rs5215	C	11	17387083	missense	5.00E-11	1.14	17463249
KCNQ1		rs231362	G	11	2670241	intron;ncRNA	3.00E-13	1.08	20581827
KIAA0672		rs10521205	A/G	17	12965825	intron-variant	0.0003	0.6	17846126
KIAA0672		rs10521204	A/C	17	12965343	intron-variant	0.0003	1.65	17846126
KIAA1604		rs10497567	A/G	1	180538737		0.0004	1.98	17846126
KLF10		-	3' UTR +10	8		--	0.009	0.81	17931948
KLF14		rs972283	G	7	130782095	--	2.00E-10	1.07	20581827
LOC646736		rs7578326	A>G	2	226155937?(	LOC646736 : Intron Variant	NA	NA	30888963
LRTM1	WNT5A	rs358806	--	3	55279372	--	0.000003	1.16	17554300
MC4R		rs17782313	C	18	57851097	--	0.02	--	19255736
MSH6		rs3136279	G/T	2	47790629	intron-variant	6.81E-05	1.8	17846126
MTHFSD		rs3751797	A/T	16	86533886	intron-variant	8.74E-05	1.6	17846126
MTNR1B		rs1387153	T	11	92940662	--	8.00E-15	1.09	20581827
NOTCH2		rs10923931	T	1	119975336	intron-variant	0.02	1.13	19020324
NOTCH2	ADAM30	rs10923931	T	1	119975336	intron	0.00000004	1.13	18372903
NPY2R		--	--	4	--	--	1.73E-04	--	17325259
PAM		rs35658696	G	5	103003107	missense,nc-transcript-variant,reference	5.30E-06	1.21	24464100
PAM		rs78408340	G	5	103003035	missense,nc-transcript-variant,reference	0.001	1.42	24464100
PPARG		rs1801282	C/G	3	12393125	intron-variant,missense,reference	1.70E-06	1.14	20424228
PPARG		rs13081389	A	3	12248301	--	0.0000002	1.24	20581827
PPARG		rs1801282	C	3	12351626	missense	0.000002	1.14	17463246
PPARG		rs1801282	C	3	12351626	missense	0.000002	1.14	17463249
PRC1		rs8042680	A	15	90978107	intron;intron	2.00E-10	1.07	20581827
PRKG2		rs980720	A/G	4	81131909	intron-variant	1.25E-05	0.52	17846126
RBMS1	ITGB6	rs7593730	--	2	160314943	--	0.00000004	0.9	20418489
RIMS1		rs10498881	C/G	6	72232903	intron-variant	0.0002	0.48	17846126
SAMD12		rs7817780	C/T	8	118404727	intron-variant	0.0002	1.85	17846126
SIRT1		rs1513287	A/G	3	113553361	intron-variant	0.0002	1.49	17846126
SLC30A8		rs13266634	C/T	8	118184783	missense,reference	5.30E-08	1.12	20424228
SLC30A8		rs3802177	G	8	117172786	UTR-3	0.00000001	1.15	20581827
SLC30A8		rs13266634	--	8	117172544	missense	0.000007	1.18	19056611
SLC30A8		rs13266634	C	8	117172544	missense	0.00000005	1.12	17463246
SLC30A8		rs13266634	C	8	117172544	missense	0.000003	1.15	17460697
SLC30A8		rs13266634	C	8	117172544	missense	0.00000005	1.12	17463249
SLC30A8		rs13266634	C	8	117172544	missense	0.00000006	1.18	17293876
SMAD7		-	-	18		--	0.007	0.62	17931948
SPECC1		rs1373147	A/T	17	20303332	intron-variant	2.79E-05	0.63	17846126
SPECC1		rs2703813	A/G	17	20212002	intron-variant	8.12E-05	0.64	17846126
SPECC1		rs2158473	C/T	17	20235777	intron-variant	0.0001	1.54	17846126
SYN2	PPARG	rs17036101	G	3	12236345	--	0.0000002	1.15	18372903
TCEB1		rs10504553	A/G	8	73964168	intron-variant	0.0002	0.56	17846126
TCF7L2		rs7903146	T/C	10	114758349	intron-variant	1.00E-48	1.37	20424228
TCF7L2		rs7903146	T	10	112998590	intron	2.00E-51	1.4	20581827
TCF7L2		rs7903146	--	10	112998590	intron	6.00E-16	1.31	19056611
TCF7L2		rs7903146	T	10	112998590	intron	3.00E-23	1.37	18372903
TCF7L2		rs4506565	T	10	112996282	intron	5.00E-12	1.36	17554300
TCF7L2		rs7903146	T	10	112998590	intron	2.00E-31	1.38	17463246
TCF7L2		rs7903146	--	10	112998590	intron	2.00E-10	1.38	17460697
TCF7L2		rs7901695	C	10	112994329	intron	1.00E-48	1.37	17463249
TCF7L2		rs7903146	T	10	112998590	intron	2.00E-34	1.65	17293876
THADA		rs7578597	T	2	43505684	missense	0.000000001	1.15	18372903
TP53		rs1042522	G	17	7579472	missense,reference,upstream-variant-2KB	0.0032	1.06	21283750
TP53INP1		rs896854	T	8	94948283	intron;nearGene-5	0.000000001	1.06	20581827
TRPS1		rs2737245	A/C	8	115646356	intron-variant	0.0002	0.67	17846126
TSPAN8	LGRF	rs1495377	G	12	71183321	--	0.000007	1.28	17554300
TSPAN8	LGRF	rs4760790	A	12	71241014	--	0.000004	1.11	20581827
TSPAN8	LGRF	rs7961581	C	12	71269322	--	0.000000001	1.09	18372903
VEGFA		rs9472138	T	6	43844025	--	0.000004	1.06	18372903
WFS1		rs10010131	G	4	6291188	intron-variant	0.001	1.12	19020324
WFS1		rs1801214	T	4	6301295	missense	0.00000003	1.13	20581827
ZBED3		rs4457053	G	5	77129124	intron	3.00E-12	1.08	20581827
ZFAND6		rs11634397	G	15	80139880	--	0.000000002	1.06	20581827
		rs10509199	G/T	10	63866054	intron-variant	1.68E-05	0.62	17846126
		rs10509195	A/C	10	63763606	--	3.30E-05	1.62	17846126
		rs1395931	A/G	2	123061397	--	6.36E-05	1.57	17846126
		rs1446732	G/T	2	133900169	--	7.38E-05	1.55	17846126
		rs10485249	C/G	6	69395295	--	7.96E-05	0.54	17846126
		rs1916412	C/T	10	63911035	--	8.35E-05	1.54	17846126
		rs1916411	C/G	10	63911073	--	8.48E-05	0.65	17846126
		rs930621	C/T	2	133944507	--	8.74E-05	1.55	17846126
		rs10509201	A/G	10	63912482	--	8.80E-05	1.53	17846126
		rs2502497	G/T	6	74632647	intron-variant	0.0001	0.43	17846126
		rs430123	A/G	5	106746032	--	0.0002	0.61	17846126
		rs10507601	A/G	13	55575243	--	0.0002	0.44	17846126
		rs994952	A/G	6	77553238	--	0.0002	1.52	17846126
		rs297765	A/G	20	4506463	--	0.0002	1.55	17846126
		rs4410442	A/G	3	111232963	--	0.0002	1.52	17846126
		rs1351916	A/T	2	139005878	--	0.0002	0.67	17846126
		rs1507666	A/T	2	123058409	--	0.0002	0.66	17846126
		rs10498934	C/T	6	82750130	--	0.0002	0.66	17846126
		rs721729	A/G	3	173471483	intron-variant	0.0002	0.65	17846126
		rs10484725	A/G	6	77559444	--	0.0002	1.75	17846126
		rs10487440	G/T	7	126336506	--	0.0002	0.59	17846126
		rs9317821	C/T	13	69536272	--	0.0002	0.67	17846126
		rs10487442	A/G	7	126423202	--	0.0003	1.68	17846126
		rs6897150	A/G	5	166473793	--	0.0003	1.6	17846126
		rs1458405	G/T	6	77554762	--	0.0003	1.54	17846126
		rs1023738	C/T	3	173485440	intron-variant	0.0003	0.67	17846126
		rs2034531	A/G	4	136223455	--	0.0003	0.59	17846126
		rs9328099	A/G	6	2437311	--	0.0004	0.63	17846126

T2DiACoD

European