A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders
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Locus_Id | Gene_Symbol | Chromosome | Homologene_Id | Gene_Name | Synonyms |
---|---|---|---|---|---|
19 | ABCA1 | 9 | 21130 | ATP binding cassette subfamily A member 1 | TGD, ABC1, CERP, ABC-1, HDLDT1 |
9619 | ABCG1 | 21 | 21022 | ATP binding cassette subfamily G member 1 | ABC8, WHITE1 |
38 | ACAT1 | 11 | 6 | acetyl-CoA acetyltransferase 1 | T2, MAT, ACAT, THIL |
2180 | ACSL1 | 4 | 37561 | acyl-CoA synthetase long-chain family member 1 | ACS1,LACS,FACL1,FACL2,LACS1,LACS2 |
6868 | ADAM17 | 2 | 2395 | ADAM metallopeptidase domain 17 | CSVP, TACE, NISBD, ADAM18, CD156B, NISBD1 |
9370 | ADIPOQ | 3 | 3525 | adiponectin, C1Q and and collagen domain containing | ACDC, ADPN, APM1, APM-1 |
177 | AGER | 6 | 883 | advanced glycosylation end product-specific receptor | RAGE |
207 | AKT1 | 14 | 3785 | v-akt murine thymoma viral oncogene homolog 1 | AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA |
213 | ALB | 4 | 405 | albumin | FDAH, ANALBA, PRO0883, PRO0903, PRO1341 |
241 | ALOX5AP | 13 | 1231 | arachidonate 5-lipoxygenase activating protein | FLAP |
23452 | ANGPTL2 | 9 | 22695 | angiopoietin like 2 | ARP2, HARP |
335 | APOA1 | 11 | 47900 | apolipoprotein A-I | apo(a) |
116519 | APOA5 | 11 | 14197 | apolipoprotein A-V | RAP3, APOAV |
55937 | APOM | 6 | 10308 | apolipoprotein M | G3a, NG20, apo-M, HSPC336 |
26060 | APPL1 | 3 | 32143 | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 | APPL MODY14 DIP13alpha |
54622 | ARL15 | 5 | 56843 | ADP ribosylation factor like GTPase 15 | ARFRP2 |
567 | B2M | 15 | 2987 | beta-2-microglobulin | IMD43 |
570 | BAAT | 9 | 1286 | bile acid-CoA:amino acid N-acyltransferase | BAT, BACAT |
650 | BMP2 | 20 | 926 | bone morphogenetic protein 2 | BDA2, BMP2A |
11132 | CAPN10 | 2 | 36323 | calpain 10 | CANP10, NIDDM1 |
6347 | CCL2 | 17 | 2245 | chemokine (C-C motif) ligand 2 | HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30 |
729230 | CCR2 | 3 | 537 | chemokine (C-C motif) receptor 2 | CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2 |
1234 | CCR5 | 3 | 37325 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, |
9332 | CD163 | 12 | 128811 | CD163 molecule | M130, MM130 |
948 | CD36 | 7 | 73871 | CD36 molecule | FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3, BDPLT10 |
920 | CD4 | 12 | 513 | CD4 molecule | CD4mut |
958 | CD40 | 20 | 954 | CD40 molecule | p50, Bp50, CDW40, TNFRSF5 |
1019 | CDK4 | 12 | 55429 | cyclin dependent kinase 4 | CMM3, PSK-J3 |
1029 | CDKN2A | 9 | 55430 | cyclin dependent kinase inhibitor 2A | ARF, MLM, P14, P16, P19, CMM2, INK4, MTS1, TP16, CDK4I, CDKN2, INK4A, MTS-1, P14ARF, P19ARF, P16INK4 |
1030 | CDKN2B | 9 | 55859 | cyclin dependent kinase inhibitor 2B | P15, MTS2, TP15, CDK4I, INK4B, p15INK4b |
100048912 | CDKN2BAS | 9 | CDKN2B antisense RNA 1 | ANRIL, p15AS, PCAT12, CDKN2BAS, CDKN2B-AS, NCRNA00089 | |
100048912 | CDKN2B-AS1 | 9 | CDKN2B antisense RNA 1 | ANRIL, p15AS, PCAT12, CDKN2BAS, CDKN2B-AS, NCRNA00089 | |
1071 | CETP | 16 | 47904 | cholesteryl ester transfer protein, plasma | BPIFF, HDLCQ10 |
1116 | CHI3L1 | 1 | 55569 | chitinase 3 like 1 | GP39, ASRT7, GP-39, YKL |
10370 | CITED2 | 6 | 4433 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | ASD8 MRG1 VSD2 MRG-1 P35SRJ |
22796 | COG2 | 1 | 7206 | component of oligomeric golgi complex 2 | LDLC |
1398 | CRK | 17 | 81850 | v-crk avian sarcoma virus CT10 oncogene homolog | p38, CRKII |
1401 | CRP | 1 | 128039 | C-reactive protein, pentraxin-related | PTX1 |
1471 | CST3 | 20 | 78 | cystatin C | ARMD11, HEL-S-2 |
6376 | CX3CL1 | 16 | 2251 | chemokine (C-X3-C motif) ligand 1 | NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin |
6374 | CXCL5 | 4 | 88672 | chemokine (C-X-C motif) ligand 5 | SCYB5, ENA-78 |
1535 | CYBA | 16 | 80 | cytochrome b-245, alpha polypeptide | p22-PHOX |
1543 | CYP1A1 | 15 | 68062 | cytochrome P450 family 1 subfamily A member 1 | AHH, AHRR, CP11, CYP1, CYPIA1, P1-450, P450-C, P450DX |
780 | DDR1 | 6 | 68212 | discoidin domain receptor tyrosine kinase 1 | CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, CD167, EDDR1, MCK10, NTRK4, PTK3A |
1717 | DHCR7 | 11 | 1042 | 7-dehydrocholesterol reductase | SLOS |
1803 | DPP4 | 2 | 3279 | dipeptidyl peptidase 4 | CD26, ADABP, ADCP2, DPPIV, TP103 |
1906 | EDN1 | 6 | 1476 | endothelin 1 | ET1, QME, PPET1, ARCND3, HDLCQ7 |
2006 | ELN | 7 | elastin | WS, WBS, SVAS | |
953 | ENTPD1 | 10 | 20423 | ectonucleoside triphosphate diphosphohydrolase 1 | CD39, SPG64, ATPDase, NTPDase-1 |
2169 | FABP2 | 4 | 107 | fatty acid binding protein 2 | FABPI, I-FABP |
2167 | FABP4 | 8 | 36067 | fatty acid binding protein 4 | aP2, ALBP, AFABP, A-FABP, HEL-S-104 |
2171 | FABP5 | 8 | 108238 | fatty acid binding protein 5 | EFABP, KFABP, E-FABP, PAFABP, PA-FABP |
26291 | FGF21 | 19 | 10428 | fibroblast growth factor 21 | |
8074 | FGF23 | 12 | 10771 | fibroblast growth factor 23 | ADHR, FGFN, HPDR2, HYPF, PHPTC |
2260 | FGFR1 | 8 | 69065 | fibroblast growth factor receptor 1 | CEK, FLG, HH2, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, FLT-2, HBGFR, N-SAM, FGFR-1, HRTFDS, bFGF-R-1 |
2286 | FKBP2 | 11 | 40604 | FK506 binding protein 2 | PPIase, FKBP-13 |
2328 | FMO3 | 1 | 128199 | flavin containing monooxygenase 3 | TMAU, FMOII, dJ127D3.1 |
2331 | FMOD | 1 | 1530 | fibromodulin | FM, SLRR2E |
3170 | FOXA2 | 20 | 7762 | forkhead box A2 | HNF3B, TCF3B |
2308 | FOXO1 | 13 | 1527 | forkhead box O1 | FKH1, FKHR, FOXO1A |
2357 | FPR1 | 19 | 20466 | formyl peptide receptor 1 | FPR, FMLP |
2695 | GIP | 17 | 3043 | gastric inhibitory polypeptide | |
2739 | GLO1 | 6 | 4880 | glyoxalase I | GLYI, GLOD1, HEL-S-74 |
2876 | GPX1 | 3 | 20155 | glutathione peroxidase 1 | GPXD, GSHPX1 |
2944 | GSTM1 | 1 | 37357 | glutathione S-transferase mu 1 | MU, H-B, GST1, GTH4, GTM1, MU-1, GSTM1-1, GSTM1a-1a, GSTM1b-1b |
2952 | GSTT1 | 22 | glutathione S-transferase theta 1 | ||
9734 | HDAC9 | 7 | 128578 | histone deacetylase 9 | HD7 HD9 HD7b HDAC HDRP MITR HDAC7 HDAC7B HDAC9B HDAC9FL |
3082 | HGF | 7 | 503 | hepatocyte growth factor | SF, HGFB, HPTA, F-TCF, DFNB39 |
3240 | HP | 16 | 121756 | haptoglobin | BP HPA1S HP2ALPHA2 |
3383 | ICAM1 | 19 | 168 | intercellular adhesion molecule 1 | BB2, CD54, P3.58 |
3606 | IL18 | 11 | 1200 | interleukin 18 | IGIF, IL-18, IL-1g, IL1 |
7850 | IL1R2 | 2 | 7783 | interleukin 1 receptor type 2 | IL1RB, CD121b, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2 |
3569 | IL6 | 7 | 502 | interleukin 6 | HGF, HSF, BSF2, IL-6, IFNB2 |
3570 | IL6R | 1 | 474 | interleukin 6 receptor | IL6Q,gp80,CD126,IL6RA,IL6RQ,IL-6RA,IL-6R-1 |
3630 | INS | 11 | 173 | insulin | IDDM, ILPR, IRDN, IDDM1, IDDM2, MODY10 |
3643 | INSR | 19 | 20090 | insulin receptor | HHF5, CD220 |
51135 | IRAK4 | 12 | 41109 | interleukin 1 receptor associated kinase 4 | IPD1,REN64,IRAK-4,NY-REN-64 |
3667 | IRS1 | 2 | 4049 | insulin receptor substrate 1 | HIRS-1 |
8660 | IRS2 | 13 | 2778 | insulin receptor substrate 2 | IRS-2 |
136259 | KLF14 | 7 | 76469 | Kruppel like factor 14 | BTEB5 |
3949 | LDLR | 19 | 55469 | low density lipoprotein receptor | FH, FHC, LDLCQ2 |
3952 | LEP | 7 | 193 | leptin | OB, OBS, LEPD |
3953 | LEPR | 1 | 1731 | leptin receptor | OBR,OB-R,CD295,LEP-R,LEPRD |
4018 | LPA | 6 | 87856 | lipoprotein, Lp(a) | LP, AK38, APOA |
4023 | LPL | 8 | 200 | lipoprotein lipase | LIPD, HDLCQ11 |
9935 | MAFB | 20 | 31315 | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | KRML, MCTO |
4282 | MIF | 22 | 55655 | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | GIF, GLIF, MMIF |
4313 | MMP2 | 16 | 3329 | matrix metallopeptidase 2 | CLG4, MONA, CLG4A, MMP-2, TBE-1, MMP-II |
4318 | MMP9 | 20 | 3659 | matrix metallopeptidase 9 | GELB, CLG4B, MMP-9, MANDP2 |
5891 | MOK | 14 | 8062 | MOK protein kinase | RAGE, RAGE1, STK30, RAGE-1 |
4353 | MPO | 17 | 55450 | myeloperoxidase | |
4524 | MTHFR | 1 | 4349 | methylenetetrahydrofolate reductase (NAD(P)H) | |
4615 | MyD88 | 3 | 1849 | myeloid differentiation primary response 88 | NA |
114548 | NLRP3 | 1 | 3600 | NLR family, pyrin domain containing 3 | AII, AVP, FCU, MWS, FCAS, CIAS1, FCAS1, NALP3, C1orf7, CLR1.1, PYPAF1, AGTAVPRL |
4846 | NOS3 | 7 | 504 | nitric oxide synthase 3 | eNOS, ECNOS |
50507 | NOX4 | 11 | 41065 | NADPH oxidase 4 | KOX, KOX-1, RENOX |
4852 | NPY | 7 | 697 | neuropeptide Y | PYY4 |
1728 | NQO1 | 16 | 695 | NAD(P)H dehydrogenase, quinone 1 | DTD, QR1, DHQU, DIA4, NMOR1, NMORI |
6696 | OPN | 4 | 20156 | secreted phosphoprotein 1 | OPN, BNSP, BSPI, ETA-1 |
142 | PARP1 | 1 | 1222 | poly(ADP-ribose) polymerase 1 | PARP, PPOL, ADPRT, ARTD1, ADPRT1, PARP-1, ADPRT, 1, pADPRT-1 |
5076 | PAX2 | 10 | 2968 | paired box 2 | FSGS7 PAPRS |
255738 | PCSK9 | 1 | 17790 | proprotein convertase subtilisin/kexin type 9 | FH3, PC9, NARC1, LDLCQ1, NARC-1, HCHOLA3 |
80310 | PDGFD | 11 | 11875 | platelet derived growth factor D | IEGF, SCDGFB, MSTP036, SCDGF-B |
5320 | PLA2G2A | 1 | 254 | phospholipase A2 group IIA | MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 |
5360 | PLTP | 20 | 4536 | phospholipid transfer protein | BPIFE, HDLCQ9 |
5444 | PON1 | 7 | 68058 | paraoxonase 1 | ESA, PON, MVCD5 |
5445 | PON2 | 7 | 385 | paraoxonase 2 | |
5446 | PON3 | 7 | 37371 | paraoxonase 3 | |
5465 | PPARA | 22 | 21047 | peroxisome proliferator activated receptor alpha | PPAR, NR1C1, hPPAR, PPARalpha |
5468 | PPARG | 3 | 7899 | peroxisome proliferator activated receptor gamma | GLM1, CIMT1, NR1C3, PPA |
5547 | PRCP | 11 | 55867 | prolylcarboxypeptidase | PCP, HUMPCP |
3275 | PRMT2 | 21 | 55587 | protein arginine methyltransferase 2 | HRMT1L1 |
5730 | PTGDS | 9 | 737 | prostaglandin D2 synthase 21kDa (brain) | PDS, PGD2, PGDS, LPGDS, PGDS2, L-PGDS |
5770 | PTPN1 | 20 | 2119 | protein tyrosine phosphatase, non-receptor type 1 | PTP1B |
5806 | PTX3 | 3 | 7500 | pentraxin 3 | TSG-14, TNFAIP5 |
5950 | RBP4 | 10 | 4908 | retinol binding protein 4 | RDCCAS, MCOPCB10 |
5972 | REN | 1 | 2184 | renin | HNFJ2 |
56729 | RETN | 19 | 10703 | resistin | ADSF, RSTN, XCP1, FIZZ3, RETN1 |
9475 | ROCK2 | 2 | 21010 | Rho associated coiled-coil containing protein kinase 2 | ROCK-II |
860 | RUNX2 | 6 | runt related transcription factor 2 | CCD, AML3, CCD1, CLCD, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2aA, CBF-alpha-1 | |
58506 | SCAF1 | 19 | 10442 | SR-related CTD-associated factor 1 | SRA1 |
949 | SCARB1 | 12 | 21132 | scavenger receptor class B member 1 | CLA1, SRB1, CLA-1, SR-BI, CD36L1, HDLQTL6 |
23411 | SIRT1 | 10 | 56556 | sirtuin 1 | SIR2, SIR2L1, SIR2alpha |
6524 | SLC5A2 | 16 | 2289 | solute carrier family 5 member 2 | SGLT2 |
50964 | SOST | 17 | 11542 | sclerostin | CDD, VBCH, SOST1 |
79689 | STEAP4 | 7 | 36422 | STEAP4 metalloreductase | TIARP, STAMP2, TNFAIP9 |
6934 | TCF7L2 | 10 | 7564 | transcription factor 7 like 2 | TCF4, TCF-4 |
7078 | TIMP3 | 22 | 36322 | TIMP metallopeptidase inhibitor 3 | SFD, K222, K222TA2, HSMRK222 |
7099 | TLR4 | 9 | 41317 | toll like receptor 4 | TOLL, CD284, TLR-4, ARMD10 |
4982 | TNFRSF11B | 8 | 1912 | tumor necrosis factor receptor superfamily member 11b | OPG, TR1, OCIF, PDB5 |
7225 | TRPC6 | 11 | 37944 | transient receptor potential cation channel subfamily C member 6 | TRP6, FSGS2 |
7295 | TXN | 9 | 128202 | thioredoxin | TRX, TRDX, TRX1 |
10628 | TXNIP | 1 | 38186 | thioredoxin interacting protein | THIF, VDUP1, HHCPA78, EST01027 |
7351 | UCP2 | 11 | 2516 | uncoupling protein 2 (mitochondrial proton carrier) | UCPH, BMIQ4, SLC25A8 |
10911 | UTS2 | 1 | 4939 | urotensin 2 | UII, U-II, UCN2, PRO1068 |
7412 | VCAM1 | 1 | 838 | vascular cell adhesion molecule 1 | CD106, INCAM-100 |
7422 | VEGFA | 6 | 2534 | vascular endothelial growth factor A | VPF, VEGF, MVCD1 |